Duke CTSI TransPop offers a wide range of assets and capabilities for investigators. These resources have been developed under and grown out of the MURDOCK Study, which began in 2007.

The MURDOCK Study offers:

  • Proposal Concept Form For prospective collaborators requesting access to the MURDOCK Study cohort, samples and data to design a research study. We offer support for developing and identifying study design, budget and funding sources. MURDOCK Study leadership reviews proposals on a rolling basis.
  • Analysis Topic Request Form For MURDOCK investigators interested in accessing data sets from the Community Registry. External collaborators or sponsors may also submit this form, but a MURDOCK investigator must be included as a co-author. The MURDOCK Analysis and Publications Committee reviews topic requests on a rolling basis.
  • Data Assets The MURDOCK Study offers access to nearly 450,000 annotated samples from more than 12,500 study participants. Samples are paired with clinical data, annual follow-up data and medical records. Each participant is geospatially mapped.
  • Registry Demographics An overview of current demographics of the MURDOCK Study Community Registry and Biorepository.
  • Data Dictionary The MURDOCK Integrated Data Repository (MIDR) contains a breadth of data collected from study visits and annual follow-up questionnaires. Data collected during the enrollment visit includes self-reported lifestyle, demographic, medication, and health information, as well as clinical measurements. Follow-up questionnaires collect updated, self-reported information on an annual basis.

TransPop’s capabilities include:

Proposal & Budget Development

The business development team offers a range of services needed to prepare and submit proposals to sponsors, including budget development, content generation and grantsmanship, and full proposal packaging.

Project Leadership

Experienced project leaders offer end-to-end study management with broad skill sets that span community engagement, study start-up, clinical operations, data management, and other functional domains.

Regulatory Support

Our local regulatory staff are available for protocol consultation or development, Institutional Review Board classification, submissions and correspondence, and maintaining compliance with Duke regulatory policies.

Cohort Identification

We can rapidly segment our registry population by numerous clinical and demographic criteria, including publicly available census data linked through geo-spatial mapping. Registry consent allows for contact as a recruitment tactic for prospective research projects.

Community Engagement & Targeted Recruitment

Our community engagement team is dedicated and well-connected across the local region and can provide strategies and tactics to meet recruitment needs, including targeted recruitment of cohorts identified from exisiting participant populations.

Clinical Operations

Our Duke-trained clinical staff of research coordinators and specialists are experienced across disease areas and related research study procedures and measures. Our operations are SOP-driven but can be tailored to a wide range of study designs and sizes.

Data Management

We offer “fit-for-purpose” data management, with services including CRF design, database development in REDCapÆ, workflow development, data entry, and quality control.

Marketing & Communications

We develop and execute study-specific communications plans, including print and digital media campaigns and tactics, suppoting study recruitment, participant retention, and public/media relations.

Bilingual Staff & Translation

We have bilingual (English & Spanish) staff in all functional areas, and offer in-house translation of study documents and recruitment materials, including validation through back-translation.

Biospecimens & Biobanking

Our biorepository includes over 429,000 specimens from over 12,500 unique participants, annotated with clinical and demographic data from our registry. We have skilled phlebotomists and established workflows for collecting, processing, and storing specimens for future analysis.

To discuss opportunities for collaboration, please email or contact Julie Eckstrand (336) 260-9802 or Karen Johnson  (919) 668-8447. All proposal ideas are reviewed and approved by MURDOCK Study leadership.

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