Director, Center for Applied Genomics & Precision Medicine
Duke University School of Medicine
Director, MEDxSchool of Medicine-Pratt School of Engineering
Professor of Medicine and Pathology, Duke University Medical Center Professor of Biomedical Engineering, Pratt School of Engineering
Dr. Ginsburg is the founding director for the Center for Applied Genomics & Precision Medicine at the Duke University Medical Center. He is also the founding director for MEDx, a partnership between the Schools of Medicine and Engineering to spark and translate innovation. He is a professor of Medicine, Pathology, and Biomedical Engineering at Duke University.
While at Duke, Dr. Ginsburg has pioneered translational genomics, the development of novel diagnostics, and precision medicine, initiating programs in genome enabled biomarker discovery, longitudinal registries with linked molecular and clinical data, biomarker-informed clinical trials, and the development of novel practice models and implementation research for the integration of genomic tools and digital health technologies into heath care delivery systems. With a strong commitment to interdisciplinary science he has led projects to develop predictive models for common complex diseases using high dimensional genomic data as well as collaborations with engineering groups to develop novel point of care sensors.
His work spans oncology, infectious diseases, cardiovascular disease and metabolic disorders, and his research is addressing the challenges for translating genomic information into medical practice using new and innovative paradigms, and the integration of personalized medicine into health care. He is an internationally recognized expert in genomics and personalized medicine with over 200 published papers, and funding from NIH, DOD, Air Force, DARPA, the Gates Foundation, and industry.
In 1990, he joined the faculty of Harvard Medical School, where he was director of Preventive Cardiology at Beth Israel Hospital and led a laboratory in applied genetics of cardiovascular diseases at Children’s Hospital. In 1997 he joined Millennium Pharmaceuticals Inc, as senior program director for cardiovascular diseases and was eventually appointed vice president of Molecular and Personalized Medicine, where he was responsible for developing pharmacogenomic strategies for therapeutics, as well as biomarkers for disease and their implementation in the drug development process. He has received a number of awards for his research accomplishments, including the Innovator in Medicine Award from Millennium in 2004, the Basic Research Achievement Award in Cardiovascular Medicine from Duke in 2005, and the ILCHUN Molecular Medicine Award from Korean Society for Biochemistry and Molecular Biology in 2014. In 2015 he was an honored speaker at the White House Champions for Change in Precision Medicine.
He is a founding member and former board member of the Personalized Medicine Coalition, a section editor for The Journal of the American College of Cardiology and an editorial advisor for Science Translational Medicine. In addition, he is the editor of Genomic and Personalized Medicine (Elsevier) published in 2012. He is a member of the Faculty of 1000. He has been a member of the Secretary of Veterans Affairs Advisory Council on Genomic Medicine, a member of the NIGMS External Scientific Panel for the Pharmacogenomics Research Network, and the National Advisory Council for Human Genome Research at NIH. He is currently an international expert panel member for Genome Canada, a member of the Board of External Experts for the National Heart, Lung and Blood Institute, and a member of the World Economic Forum’s Global Agenda Council on The Future of the Health Sector.
He is also a member of the Advisory Council for the National Center for Advancing Translational Sciences at NIH and is the Vice Chair for the Cures Acceleration Network Board. He is co-chair of the Institute of Medicine’s Roundtable on Translating Genome-Based Research for Health and co-chair of the IOM/NIH Global Genomic Medicine Collaborative.He received his MD and PhD in biophysics from Boston University and completed an internal medicine residency at Beth Israel Hospital in Boston, MA. Subsequently, he pursued postdoctoral training in clinical cardiovascular medicine at Beth Israel Hospital and in molecular biology at Children’s Hospital as a Bugher Foundation Fellow of the American Heart Association.